Viral vectors based on bidirectional cell-specific mammalian promoters and transcriptional amplification strategy for use in vitro and in vivo

BACKGROUND: Using cell-type-specific promoters to restrict gene expression to particular cells is an attractive approach for gene therapy, but often hampered by insufficient transcriptional activity of these promoters. Previous studies have shown that transcriptional amplification strategy (TAS) can...

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Detalles Bibliográficos
Autores principales: Liu, Beihui, Paton, Julian F, Kasparov, Sergey
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396617/
https://www.ncbi.nlm.nih.gov/pubmed/18485188
http://dx.doi.org/10.1186/1472-6750-8-49

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396617/
https://www.ncbi.nlm.nih.gov/pubmed/18485188
http://dx.doi.org/10.1186/1472-6750-8-49

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