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Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients

BACKGROUND: The epidermal growth factor (EGF) and EGF receptor (EGFR) families play important roles in the hyperplastic growth of several tissues as well as tumor growth. Since synovial hyperplasia in rheumatoid arthritis (RA) resembles a tumor, involvement of the EGF/EGFR families in RA pathology h...

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Detalles Bibliográficos
Autores principales: Yamane, Shoji, Ishida, Satoru, Hanamoto, Yukie, Kumagai, Ken-ichi, Masuda, Riako, Tanaka, Konagi, Shiobara, Noriyuki, Yamane, Noriko, Mori, Toshihito, Juji, Takuo, Fukui, Naoshi, Itoh, Tsunetoshi, Ochi, Takahiro, Suzuki, Ryuji
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396620/
https://www.ncbi.nlm.nih.gov/pubmed/18439312
http://dx.doi.org/10.1186/1476-9255-5-5