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The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching

Blood vessel formation requires the integrated regulation of endothelial cell proliferation and branching morphogenesis, but how this coordinated regulation is achieved is not well understood. Flt-1 (vascular endothelial growth factor [VEGF] receptor 1) is a high affinity VEGF-A receptor whose loss...

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Detalles Bibliográficos
Autores principales: Kappas, Nicholas C., Zeng, Gefei, Chappell, John C., Kearney, Joseph B., Hazarika, Surovi, Kallianos, Kimberly G., Patterson, Cam, Annex, Brian H., Bautch, Victoria L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396811/
https://www.ncbi.nlm.nih.gov/pubmed/18504303
http://dx.doi.org/10.1083/jcb.200709114