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DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release

Schizophrenia is one of the most debilitating neuropsychiatric disorders, affecting 0.5–1.0% of the population worldwide. Its pathology, attributed to defects in synaptic transmission, remains elusive. The dystrobrevin-binding protein 1 (DTNBP1) gene, which encodes a coiled-coil protein, dysbindin,...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Wei, Feng, Ya-Qin, Hao, Chan-Juan, Guo, Xiao-Li, He, Xin, Zhou, Zhi-Yong, Guo, Ning, Huang, Hong-Ping, Xiong, Wei, Zheng, Hui, Zuo, Pan-Li, Zhang, Claire Xi, Li, Wei, Zhou, Zhuan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396815/
https://www.ncbi.nlm.nih.gov/pubmed/18504299
http://dx.doi.org/10.1083/jcb.200711021