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Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease

BACKGROUND: COPD is characterised by loss of alveolar elastic fibers and by lack of effective repair. Elastic fibers are assembled at cell surfaces by elastin binding protein (EBP), a molecular chaperone whose function can be reversibility inhibited by chondroitin sulphate of matrix proteoglycans su...

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Detalles Bibliográficos
Autores principales: Merrilees, Mervyn J, Ching, Pamela ST, Beaumont, Brent, Hinek, Aleksander, Wight, Thomas N, Black, Peter N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397404/
https://www.ncbi.nlm.nih.gov/pubmed/18485243
http://dx.doi.org/10.1186/1465-9921-9-41