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Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain
BACKGROUND: AMP-activated protein kinase (AMPK) is a known physiological cellular energy sensor and becomes phosphorylated at Thr-172 in response to changes in cellular ATP levels. Activated AMPK acts as either an inducer or suppressor of apoptosis depending on the severity of energy stress and the...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397440/ https://www.ncbi.nlm.nih.gov/pubmed/18474106 http://dx.doi.org/10.1186/1476-4598-7-37 |