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Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain

BACKGROUND: AMP-activated protein kinase (AMPK) is a known physiological cellular energy sensor and becomes phosphorylated at Thr-172 in response to changes in cellular ATP levels. Activated AMPK acts as either an inducer or suppressor of apoptosis depending on the severity of energy stress and the...

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Detalles Bibliográficos
Autores principales:	Mukherjee, Purna, Mulrooney, Tiernan J, Marsh, Jeremy, Blair, Derek, Chiles, Thomas C, Seyfried, Thomas N
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397440/ https://www.ncbi.nlm.nih.gov/pubmed/18474106 http://dx.doi.org/10.1186/1476-4598-7-37

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