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Computational identification of obligatorily autocatalytic replicators embedded in metabolic networks

BACKGROUND: If chemical A is necessary for the synthesis of more chemical A, then A has the power of replication (such systems are known as autocatalytic systems). We provide the first systems-level analysis searching for small-molecular autocatalytic components in the metabolisms of diverse organis...

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Detalles Bibliográficos
Autores principales: Kun, Ádám, Papp, Balázs, Szathmáry, Eörs
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397503/
https://www.ncbi.nlm.nih.gov/pubmed/18331628
http://dx.doi.org/10.1186/gb-2008-9-3-r51