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Functionally important segments in proteins dissected using Gene Ontology and geometric clustering of peptide fragments

We have developed a geometric clustering algorithm using backbone φ,ψ angles to group conformationally similar peptide fragments of any length. By labeling each fragment in the cluster with the level-specific Gene Ontology 'molecular function' term of its protein, we are able to compute st...

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Detalles Bibliográficos
Autores principales: Manikandan, Karuppasamy, Pal, Debnath, Ramakumar, Suryanarayanarao, Brener, Nathan E, Iyengar, Sitharama S, Seetharaman, Guna
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397504/
https://www.ncbi.nlm.nih.gov/pubmed/18331637
http://dx.doi.org/10.1186/gb-2008-9-3-r52