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Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

INTRODUCTION: The phenotypic and functional differences between cells that initiate human breast tumors (cancer stem cells) and those that comprise the tumor bulk are difficult to study using only primary tumor tissue. We embarked on this study hypothesizing that breast cancer cell lines would conta...

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Detalles Bibliográficos
Autores principales: Fillmore, Christine M, Kuperwasser, Charlotte
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397524/
https://www.ncbi.nlm.nih.gov/pubmed/18366788
http://dx.doi.org/10.1186/bcr1982