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NHERF1: molecular brake on the PI3K pathway in breast cancer

The adaptor protein NHERF1/EBP50 (Na/H exchanger regulatory factor 1/ezrin-radixin-moesin-binding phosphoprotein 50) emerged recently as an important player in breast cancer progression. Consisting of two tandem PDZ domains linked to a carboxyl-terminal ezrin-binding region, NHERF1 assembles macromo...

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Detalles Bibliográficos
Autor principal: Georgescu, Maria-Magdalena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397532/
https://www.ncbi.nlm.nih.gov/pubmed/18430260
http://dx.doi.org/10.1186/bcr1992