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Expression patterns and prognostic value of Bag-1 and Bcl-2 in breast cancer

INTRODUCTION: Bcl-2 antanogene-1 (Bag-1) binds the anti-apoptotic mediator Bcl-2, and enhances its activity. Bcl-2 and Bag-1 are associated with chemotherapy resistance in cancer cells. Drugs that target Bcl-2 are currently in clinical development. The purpose of the present study was to examine exp...

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Detalles Bibliográficos
Autores principales: Nadler, Yasmine, Camp, Robert L, Giltnane, Jennifer M, Moeder, Christopher, Rimm, David L, Kluger, Harriet M, Kluger, Yuval
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397537/
https://www.ncbi.nlm.nih.gov/pubmed/18430249
http://dx.doi.org/10.1186/bcr1998