TNK2 preserves epidermal growth factor receptor expression on the cell surface and enhances migration and invasion of human breast cancer cells

INTRODUCTION: Amplification of the TNK2 gene in primary tumours correlates with poor prognosis. In accordance, TNK2 overexpression was shown to promote invasion of cancer cells – but the mechanism by which TNK2 mediates these effects is unresolved. TNK2 was suggested to regulate Cdc42-driven migrati...

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Detalles Bibliográficos
Autores principales: Howlin, Jillian, Rosenkvist, Jeanette, Andersson, Tommy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397538/
https://www.ncbi.nlm.nih.gov/pubmed/18435854
http://dx.doi.org/10.1186/bcr2087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397538/
https://www.ncbi.nlm.nih.gov/pubmed/18435854
http://dx.doi.org/10.1186/bcr2087

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