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TNK2 preserves epidermal growth factor receptor expression on the cell surface and enhances migration and invasion of human breast cancer cells

INTRODUCTION: Amplification of the TNK2 gene in primary tumours correlates with poor prognosis. In accordance, TNK2 overexpression was shown to promote invasion of cancer cells – but the mechanism by which TNK2 mediates these effects is unresolved. TNK2 was suggested to regulate Cdc42-driven migrati...

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Detalles Bibliográficos
Autores principales:	Howlin, Jillian, Rosenkvist, Jeanette, Andersson, Tommy
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397538/ https://www.ncbi.nlm.nih.gov/pubmed/18435854 http://dx.doi.org/10.1186/bcr2087

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