Tumor Cell Phenotype Is Sustained by Selective MAPK Oxidation in Mitochondria

Mitochondria are major cellular sources of hydrogen peroxide (H(2)O(2)), the production of which is modulated by oxygen availability and the mitochondrial energy state. An increase of steady-state cell H(2)O(2) concentration is able to control the transition from proliferating to quiescent phenotype...

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Detalles Bibliográficos
Autores principales: Galli, Soledad, Antico Arciuch, Valeria Gabriela, Poderoso, Cecilia, Converso, Daniela Paola, Zhou, Qiongqiong, de Kier Joffé, Elisa Bal, Cadenas, Enrique, Boczkowski, Jorge, Carreras, María Cecilia, Poderoso, Juan José
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398776/
https://www.ncbi.nlm.nih.gov/pubmed/18545666
http://dx.doi.org/10.1371/journal.pone.0002379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398776/
https://www.ncbi.nlm.nih.gov/pubmed/18545666
http://dx.doi.org/10.1371/journal.pone.0002379

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