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HIV-1 Pre-Integration Complexes Selectively Target Decondensed Chromatin in the Nuclear Periphery

Integration of the double-stranded DNA copy of the HIV-1 genome into host chromosomal DNA is a requirement for efficient viral replication. Integration preferentially occurs within active transcription units, however chromosomal site specificity does not correlate with any strong primary sequence. T...

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Detalles Bibliográficos
Autores principales: Albanese, Alberto, Arosio, Daniele, Terreni, Mariaelena, Cereseto, Anna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398779/
https://www.ncbi.nlm.nih.gov/pubmed/18545681
http://dx.doi.org/10.1371/journal.pone.0002413