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HIV-1 Pre-Integration Complexes Selectively Target Decondensed Chromatin in the Nuclear Periphery
Integration of the double-stranded DNA copy of the HIV-1 genome into host chromosomal DNA is a requirement for efficient viral replication. Integration preferentially occurs within active transcription units, however chromosomal site specificity does not correlate with any strong primary sequence. T...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398779/ https://www.ncbi.nlm.nih.gov/pubmed/18545681 http://dx.doi.org/10.1371/journal.pone.0002413 |