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A Genomic-Based Approach Combining In Vivo Selection in Mice to Identify a Novel Virulence Gene in Leishmania

BACKGROUND: Infection with Leishmania results in a broad spectrum of pathologies where L. infantum and L. donovani cause fatal visceral leishmaniasis and L. major causes destructive cutaneous lesions. The identification and characterization of Leishmania virulence genes may define the genetic basis...

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Detalles Bibliográficos
Autores principales: Zhang, Wen-Wei, Peacock, Christopher S., Matlashewski, Greg
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398785/
https://www.ncbi.nlm.nih.gov/pubmed/18545684
http://dx.doi.org/10.1371/journal.pntd.0000248