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Fast renal trapping of porcine Luteinizing Hormone (pLH) shown by (123)I-scintigraphic imaging in rats explains its short circulatory half-life

BACKGROUND: Sugar moieties of gonadotropins play no primary role in receptor binding but they strongly affect their circulatory half-life and consequently their in vivo biopotencies. In order to relate more precisely hepatic trapping of these glycoproteic hormones with their circulatory half-life, w...

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Detalles Bibliográficos
Autores principales: Klett, Danièle, Bernard, Serge, Lecompte, François, Leroux, Hervé, Magallon, Thierry, Locatelli, Alain, Lepape, Alain, Combarnous, Yves
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC239891/
https://www.ncbi.nlm.nih.gov/pubmed/14585104
http://dx.doi.org/10.1186/1477-7827-1-64