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IGF-1/IGFBP-1 increases blastocyst formation and total blastocyst cell number in mouse embryo culture and facilitates the establishment of a stem-cell line

BACKGROUND: Apoptosis occurs frequently for blastocysts cultured in vitro, where conditions are suboptimal to those found in the natural environment. Insulin-like growth factor-1 (IGF-1) plays an important role in preventing apoptosis in the early development of the embryo, as well as in the progres...

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Detalles Bibliográficos
Autores principales: Lin, Ta-Chin, Yen, Jui-Mei, Gong, Kun-Bing, Hsu, Teng-Tsao, Chen, Lih-Ren
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC239990/
https://www.ncbi.nlm.nih.gov/pubmed/14499003
http://dx.doi.org/10.1186/1471-2121-4-14