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In utero recombinant adeno-associated virus gene transfer in mice, rats, and primates

BACKGROUND: Gene transfer into the amniotic fluid using recombinant adenovirus vectors was shown previously to result in high efficiency transfer of transgenes into the lungs and intestines. Adenovirus mediated in utero gene therapy, however, resulted in expression of the transgene for less than 30...

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Detalles Bibliográficos
Autores principales: Garrett, Deiadra J, Larson, Janet E, Dunn, Daisy, Marrero, Luis, Cohen, J Craig
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC239997/
https://www.ncbi.nlm.nih.gov/pubmed/14519209
http://dx.doi.org/10.1186/1472-6750-3-16