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Saturated Fatty Acids Modulate Cell Response to DNA Damage: Implication for Their Role in Tumorigenesis

DNA damage triggers a network of signaling events that leads to cell cycle arrest or apoptosis. This DNA damage response acts as a mechanism to prevent cancer development. It has been reported that fatty acids (FAs) synthesis is increased in many human tumors while inhibition of fatty acid synthase...

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Detalles Bibliográficos
Autores principales: Zeng, Li, Wu, Guang-Zhi, Goh, Kim Jee, Lee, Yew Mun, Ng, Chuo Chung, You, Ang Ben, Wang, Jianhe, Jia, Deyong, Hao, Aijun, Yu, Qiang, Li, Baojie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2402972/
https://www.ncbi.nlm.nih.gov/pubmed/18523653
http://dx.doi.org/10.1371/journal.pone.0002329