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Lack of Interferon (IFN) Response to T7 Transcribed pppG (n)(n = 2,3)-shRNA
RNA interference (RNAi) mediated by siRNAs has proved to be a highly effective gene silencing mechanism with great potential for gene therapeutic applications. However, siRNA agents have been shown to exert non-target-related biological effects and toxicities, including immune stimulation. Specifica...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis Group
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2403744/ https://www.ncbi.nlm.nih.gov/pubmed/18066904 http://dx.doi.org/10.1080/15257770701503647 |