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Ocular biodistribution of bevasiranib following a single intravitreal injection to rabbit eyes

PURPOSE: The primary objective of these investigations was to determine the ocular biodistribution of bevasiranib, a small interfering RNA (siRNA) targeting vascular endothelial growth factor A (VEGF-A), following a single intravitreal injection to rabbit eyes. METHODS: A tissue distribution and pha...

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Detalles Bibliográficos
Autores principales: Dejneka, Nadine S., Wan, Shanhong, Bond, Ottrina S., Kornbrust, Douglas J., Reich, Samuel J.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2405815/
https://www.ncbi.nlm.nih.gov/pubmed/18523657