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Stylus: A System for Evolutionary Experimentation Based on a Protein/Proteome Model with Non-Arbitrary Functional Constraints

The study of protein evolution is complicated by the vast size of protein sequence space, the huge number of possible protein folds, and the extraordinary complexity of the causal relationships between protein sequence, structure, and function. Much simpler model constructs may therefore provide an...

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Detalles Bibliográficos
Autores principales: Axe, Douglas D., Dixon, Brendan W., Lu, Philip
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2405935/
https://www.ncbi.nlm.nih.gov/pubmed/18523658
http://dx.doi.org/10.1371/journal.pone.0002246