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Stylus: A System for Evolutionary Experimentation Based on a Protein/Proteome Model with Non-Arbitrary Functional Constraints
The study of protein evolution is complicated by the vast size of protein sequence space, the huge number of possible protein folds, and the extraordinary complexity of the causal relationships between protein sequence, structure, and function. Much simpler model constructs may therefore provide an...
Autores principales: | Axe, Douglas D., Dixon, Brendan W., Lu, Philip |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2405935/ https://www.ncbi.nlm.nih.gov/pubmed/18523658 http://dx.doi.org/10.1371/journal.pone.0002246 |
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