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CRA-1 Uncovers a Double-Strand Break-Dependent Pathway Promoting the Assembly of Central Region Proteins on Chromosome Axes During C. elegans Meiosis

The synaptonemal complex (SC), a tripartite proteinaceous structure that forms between homologous chromosomes during meiosis, is crucial for faithful chromosome segregation. Here we identify CRA-1, a novel and conserved protein that is required for the assembly of the central region of the SC during...

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Detalles Bibliográficos
Autores principales: Smolikov, Sarit, Schild-Prüfert, Kristina, Colaiácovo, Mónica P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408554/
https://www.ncbi.nlm.nih.gov/pubmed/18535664
http://dx.doi.org/10.1371/journal.pgen.1000088