L-Type Ca(2+) Channel Function Is Linked to Dystrophin Expression in Mammalian Muscle

BACKGROUND: In dystrophic mdx skeletal muscle, aberrant Ca(2+) homeostasis and fibre degeneration are found. The absence of dystrophin in models of Duchenne muscular dystrophy (DMD) has been connected to altered ion channel properties e.g. impaired L-type Ca(2+) currents. In regenerating mdx muscle,...

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Detalles Bibliográficos
Autores principales: Friedrich, Oliver, von Wegner, Frederic, Chamberlain, Jeffrey S., Fink, Rainer H. A., Rohrbach, Petra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408559/
https://www.ncbi.nlm.nih.gov/pubmed/18516256
http://dx.doi.org/10.1371/journal.pone.0001762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408559/
https://www.ncbi.nlm.nih.gov/pubmed/18516256
http://dx.doi.org/10.1371/journal.pone.0001762

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