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Whole tumor antigen vaccination using dendritic cells: Comparison of RNA electroporation and pulsing with UV-irradiated tumor cells

Because of the lack of full characterization of tumor associated antigens for solid tumors, whole antigen use is a convenient approach to tumor vaccination. Tumor RNA and apoptotic tumor cells have been used as a source of whole tumor antigen to prepare dendritic cell (DC) based tumor vaccines, but...

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Detalles Bibliográficos
Autores principales: Benencia, Fabian, Courrèges, Maria C, Coukos, George
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408561/
https://www.ncbi.nlm.nih.gov/pubmed/18445282
http://dx.doi.org/10.1186/1479-5876-6-21