High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies

BACKGROUND: Epithelial growth factor receptor (EGFR) and KRAS mutation status have been reported as predictive markers of tumour response to EGFR inhibitors. High resolution melting (HRM) analysis is an attractive screening method for the detection of both known and unknown mutations as it is rapid...

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Detalles Bibliográficos
Autores principales: Do, Hongdo, Krypuy, Michael, Mitchell, Paul L, Fox, Stephen B, Dobrovic, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408599/
https://www.ncbi.nlm.nih.gov/pubmed/18495026
http://dx.doi.org/10.1186/1471-2407-8-142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408599/
https://www.ncbi.nlm.nih.gov/pubmed/18495026
http://dx.doi.org/10.1186/1471-2407-8-142

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