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High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies
BACKGROUND: Epithelial growth factor receptor (EGFR) and KRAS mutation status have been reported as predictive markers of tumour response to EGFR inhibitors. High resolution melting (HRM) analysis is an attractive screening method for the detection of both known and unknown mutations as it is rapid...
Autores principales: | Do, Hongdo, Krypuy, Michael, Mitchell, Paul L, Fox, Stephen B, Dobrovic, Alexander |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408599/ https://www.ncbi.nlm.nih.gov/pubmed/18495026 http://dx.doi.org/10.1186/1471-2407-8-142 |
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