Cargando…
Sequence features of HLA-DRB1 locus define putative basis for gene conversion and point mutations
BACKGROUND: HLA/MHC class II molecules show high degree of polymorphism in the human population. The individual polymorphic motifs have been suggested to be propagated and mixed by transfer of genetic material (recombination, gene conversion) between alleles, but no clear molecular basis for this ha...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408603/ https://www.ncbi.nlm.nih.gov/pubmed/18489735 http://dx.doi.org/10.1186/1471-2164-9-228 |