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Sequence features of HLA-DRB1 locus define putative basis for gene conversion and point mutations

BACKGROUND: HLA/MHC class II molecules show high degree of polymorphism in the human population. The individual polymorphic motifs have been suggested to be propagated and mixed by transfer of genetic material (recombination, gene conversion) between alleles, but no clear molecular basis for this ha...

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Detalles Bibliográficos
Autores principales:	von Salomé, Jenny, Kukkonen, Jyrki P
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408603/ https://www.ncbi.nlm.nih.gov/pubmed/18489735 http://dx.doi.org/10.1186/1471-2164-9-228

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