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A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins

BACKGROUND: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent a fully accurate substitution model for proteins characterized by a biased amino acid composition. This problem has been...

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Detalles Bibliográficos
Autores principales: Brick, Kevin, Pizzi, Elisabetta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408606/
https://www.ncbi.nlm.nih.gov/pubmed/18485187
http://dx.doi.org/10.1186/1471-2105-9-236