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NO-Donating NSAIDs, PPARδ, and Cancer: Does PPARδ Contribute to Colon Carcinogenesis?

The chemopreventive NO-donating NSAIDs (NO-NSAIDs; NSAIDs with an NO-releasing moiety) modulate PPARδ and offer the opportunity to revisit the controversial role of PPARδ in carcinogenesis (several papers report that PPARδ either promotes or inhibits cancer). This review summarizes the pharmacology...

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Detalles Bibliográficos
Autores principales: Mackenzie, Gerardo G., Rasheed, Shaheen, Wertheim, William, Rigas, Basil
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408682/
https://www.ncbi.nlm.nih.gov/pubmed/18528523
http://dx.doi.org/10.1155/2008/919572