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PDGF-driven proliferation, migration, and IL8 chemokine secretion in human corneal fibroblasts involve JAK2-STAT3 signaling pathway

PURPOSE: Platelet-derived growth factor (PDGF) is associated with corneal fibroblast migration and proliferation and plays an important role in corneal wound healing. However, the intracellular mechanisms of PDGF-mediated functions in corneal fibroblasts are poorly understood. We tested the hypothes...

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Detalles Bibliográficos
Autores principales: Vij, Neeraj, Sharma, Ajay, Thakkar, Mahesh, Sinha, Sunilima, Mohan, Rajiv R.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408775/
https://www.ncbi.nlm.nih.gov/pubmed/18523665