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Membrane-type 1 matrix metalloproteinase-mediated progelatinase A activation in non-tumorigenic and tumorigenic humaneratinocytes

Elevated expression of type IV collagenases (MMP-2 and MMP-9) has been strongly correlated with tumour progression and metastasis in various tumours. Here, we analysed expression and activation of these MMPs in non-tumourigenic HaCaT cells and the malignant HaCaT variant II-4 (rt). In monolayer cult...

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Detalles Bibliográficos
Autores principales: Baumann, P, Zigrino, P, Mauch, C, Breitkreutz, D, Nischt, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408778/
https://www.ncbi.nlm.nih.gov/pubmed/11044366
http://dx.doi.org/10.1054/bjoc.2000.1454