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Inhibition of transcription factor nuclear factor-κB by a mutant inhibitor-κBα attenuates resistance of human head and neck squamous cell carcinoma to TNF-α caspase-mediated cell death

Tumour necrosis factor-α (TNF-α) is a cytokine that can induce cell death of different cancers via a cellular cascade of proteases, the caspases. However, TNF-α has been detected in tumour and serum of patients with head and neck squamous cell carcinoma (HNSCC), and tumour cell lines derived from th...

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Detalles Bibliográficos
Autores principales: Duffey, D C, Crowl-Bancroft, C V, Chen, Z, Ondrey, F G, Nejad-Sattari, M, Dong, G, Van Waes, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408789/
https://www.ncbi.nlm.nih.gov/pubmed/11044363
http://dx.doi.org/10.1054/bjoc.2000.1423