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Butyrate down-regulates CD44 transcription and liver colonisation in a highly metastatic human colon carcinoma cell line
Over-expression of the adhesion molecule CD44 and its splice variants, especially CD44v6, is associated with poor prognosis and metastasis. We aimed at regulating the expression of CD44 in the highly metastatic human colon cancer cell line HM7 and thereby affecting its metastatic ability. HM7 cells...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408907/ https://www.ncbi.nlm.nih.gov/pubmed/12439723 http://dx.doi.org/10.1038/sj.bjc.6600574 |