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Butyrate down-regulates CD44 transcription and liver colonisation in a highly metastatic human colon carcinoma cell line

Over-expression of the adhesion molecule CD44 and its splice variants, especially CD44v6, is associated with poor prognosis and metastasis. We aimed at regulating the expression of CD44 in the highly metastatic human colon cancer cell line HM7 and thereby affecting its metastatic ability. HM7 cells...

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Detalles Bibliográficos
Autores principales: Barshishat, M, Levi, I, Benharroch, D, Schwartz, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408907/
https://www.ncbi.nlm.nih.gov/pubmed/12439723
http://dx.doi.org/10.1038/sj.bjc.6600574