Drug Metabolism in Human Brain: High Levels of Cytochrome P4503A43 in Brain and Metabolism of Anti-Anxiety Drug Alprazolam to Its Active Metabolite

Cytochrome P450 (P450) is a super-family of drug metabolizing enzymes. P450 enzymes have dual function; they can metabolize drugs to pharmacologically inactive metabolites facilitating their excretion or biotransform them to pharmacologically active metabolites which may have longer half-life than t...

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Detalles Bibliográficos
Autores principales: Agarwal, Varsha, Kommaddi, Reddy P., Valli, Khader, Ryder, Daniel, Hyde, Thomas M., Kleinman, Joel E., Strobel, Henry W., Ravindranath, Vijayalakshmi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408964/
https://www.ncbi.nlm.nih.gov/pubmed/18545703
http://dx.doi.org/10.1371/journal.pone.0002337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408964/
https://www.ncbi.nlm.nih.gov/pubmed/18545703
http://dx.doi.org/10.1371/journal.pone.0002337

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