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An IFN-γ-IL-18 Signaling Loop Accelerates Memory CD8(+) T Cell Proliferation

Rapid proliferation is one of the important features of memory CD8(+) T cells, ensuring rapid clearance of reinfection. Although several cytokines such as IL-15 and IL-7 regulate relatively slow homeostatic proliferation of memory T cells during the maintenance phase, it is unknown how memory T cell...

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Detalles Bibliográficos
Autores principales: Iwai, Yoshiko, Hemmi, Hiroaki, Mizenina, Olga, Kuroda, Shoko, Suda, Koji, Steinman, Ralph M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408965/
https://www.ncbi.nlm.nih.gov/pubmed/18545704
http://dx.doi.org/10.1371/journal.pone.0002404