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Deciphering the Ubiquitin-Mediated Pathway in Apicomplexan Parasites: A Potential Strategy to Interfere with Parasite Virulence

BACKGROUND: Reversible modification of proteins through the attachment of ubiquitin or ubiquitin-like modifiers is an essential post-translational regulatory mechanism in eukaryotes. The conjugation of ubiquitin or ubiquitin-like proteins has been demonstrated to play roles in growth, adaptation and...

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Detalles Bibliográficos
Autores principales: Ponts, Nadia, Yang, Jianfeng, Chung, Duk-Won Doug, Prudhomme, Jacques, Girke, Thomas, Horrocks, Paul, Le Roch, Karine G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408969/
https://www.ncbi.nlm.nih.gov/pubmed/18545708
http://dx.doi.org/10.1371/journal.pone.0002386