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Group B Streptococcal β-Hemolysin/Cytolysin Directly Impairs Cardiomyocyte Viability and Function

BACKGROUND: Group B Streptococcus (GBS) is a leading cause of neonatal sepsis where myocardial dysfunction is an important contributor to poor outcome. Here we study the effects of the GBS pore-forming β-hemolysin/cytolysin (Bh/c) exotoxin on cardiomyocyte viability, contractility, and calcium trans...

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Detalles Bibliográficos
Autores principales: Hensler, Mary E., Miyamoto, Shigeki, Nizet, Victor
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409074/
https://www.ncbi.nlm.nih.gov/pubmed/18560574
http://dx.doi.org/10.1371/journal.pone.0002446