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Lipoteichoic acid may affect the pathogenesis of PBC-like bile duct damage and might be involved in systemic multifocal epithelial inflammations in chronic colitis-harboring TCRα(−/−) × AIM(−/−) mice

BACKGROUND: Chronic colitis-harboring TCRα(−/−) × AIM(−/−) mice showed PBC-like bile duct damage in the liver. Bacterial infection is one of the candidates for the pathogenesis of PBC. We demonstrated that the bacterial cell wall component lipotheicoic acid (LTA)was detected at sites of inflammation...

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Detalles Bibliográficos
Autores principales: Haruta, Ikuko, Hashimoto, Etsuko, Shibata, Noriyuki, Kato, Yoichiro, Kobayashi, Makio, Shiratori, Keiko
Formato: Texto
Lenguaje:English
Publicado: Informa Healthcare 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409170/
https://www.ncbi.nlm.nih.gov/pubmed/17612899
http://dx.doi.org/10.1080/08916930701402392