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Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice

BACKGROUND: The role of angiotensin II type 2 receptor (AT2) in pulmonary fibrosis is unknown. To evaluate the influence of angiotensin II type 1 receptor (AT1) and AT2 antagonists in a mouse model of bleomycin (BLM)-induced pulmonary fibrosis. METHODS: We examined effects of the AT1 antagonist (AT1...

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Detalles Bibliográficos
Autores principales: Waseda, Yuko, Yasui, Masahide, Nishizawa, Yoriko, Inuzuka, Kanako, Takato, Hazuki, Ichikawa, Yukari, Tagami, Atsuro, Fujimura, Masaki, Nakao, Shinji
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409315/
https://www.ncbi.nlm.nih.gov/pubmed/18500976
http://dx.doi.org/10.1186/1465-9921-9-43