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Characterization of two heparan sulphate-binding sites in the mycobacterial adhesin Hlp

BACKGROUND: The histone-like Hlp protein is emerging as a key component in mycobacterial pathogenesis, being involved in the initial events of host colonization by interacting with laminin and glycosaminoglycans (GAGs). In the present study, nuclear magnetic resonance (NMR) was used to map the bindi...

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Detalles Bibliográficos
Autores principales: Portugal, Michelle I, Todeschini, Adriane R, de Lima, Cristiana S, Silva, Carlos AM, Mohana-Borges, Ronaldo, Ottenhoff, Tom HM, Mendonça-Previato, Lucia, Previato, Jose O, Pessolani, Maria CV
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409343/
https://www.ncbi.nlm.nih.gov/pubmed/18482453
http://dx.doi.org/10.1186/1471-2180-8-75