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Characterization of two heparan sulphate-binding sites in the mycobacterial adhesin Hlp
BACKGROUND: The histone-like Hlp protein is emerging as a key component in mycobacterial pathogenesis, being involved in the initial events of host colonization by interacting with laminin and glycosaminoglycans (GAGs). In the present study, nuclear magnetic resonance (NMR) was used to map the bindi...
Autores principales: | Portugal, Michelle I, Todeschini, Adriane R, de Lima, Cristiana S, Silva, Carlos AM, Mohana-Borges, Ronaldo, Ottenhoff, Tom HM, Mendonça-Previato, Lucia, Previato, Jose O, Pessolani, Maria CV |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409343/ https://www.ncbi.nlm.nih.gov/pubmed/18482453 http://dx.doi.org/10.1186/1471-2180-8-75 |
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