Precision-mapping and statistical validation of quantitative trait loci by machine learning

BACKGROUND: We introduce a QTL-mapping algorithm based on Statistical Machine Learning (SML) that is conceptually quite different to existing methods as there is a strong focus on generalisation ability. Our approach combines ridge regression, recursive feature elimination, and estimation of general...

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Detalles Bibliográficos
Autores principales: Bedo, Justin, Wenzl, Peter, Kowalczyk, Adam, Kilian, Andrzej
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409372/
https://www.ncbi.nlm.nih.gov/pubmed/18452626
http://dx.doi.org/10.1186/1471-2156-9-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409372/
https://www.ncbi.nlm.nih.gov/pubmed/18452626
http://dx.doi.org/10.1186/1471-2156-9-35

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