Farnesyl transferase inhibitors induce extended remissions in transgenic mice with mature B cell lymphomas

BACKGROUND: We have used a mouse model based on overexpression of c-Myc in B cells genetically engineered to be self-reactive to test the hypothesis that farnesyl transferase inhibitors (FTIs) can effectively treat mature B cell lymphomas. FTIs are undergoing clinical trials to treat both lymphoid a...

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Detalles Bibliográficos
Autores principales: Field, Kenneth A, Charoenthongtrakul, Soratree, Bishop, J Michael, Refaeli, Yosef
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409375/
https://www.ncbi.nlm.nih.gov/pubmed/18489761
http://dx.doi.org/10.1186/1476-4598-7-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409375/
https://www.ncbi.nlm.nih.gov/pubmed/18489761
http://dx.doi.org/10.1186/1476-4598-7-39

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