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Cyclin D1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients

Antioestrogen treatment by tamoxifen is a well-established adjuvant therapy for oestrogen receptor-alpha (ERα) positive breast cancer. Despite ERα expression some tumours do not respond to tamoxifen and we therefore delineated the potential link between the cell cycle regulator and ERα co-factor, cy...

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Detalles Bibliográficos
Autores principales: Stendahl, M, Kronblad, Å, Rydén, L, Emdin, S, Bengtsson, N O, Landberg, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409465/
https://www.ncbi.nlm.nih.gov/pubmed/15138475
http://dx.doi.org/10.1038/sj.bjc.6601831