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Molecular alterations in apoptotic pathways after PKB/Akt-mediated chemoresistance in NCI H460 cells
Protein kinase B/Akt has been described as a central mediator of antiapoptotic signals in cancer cells. Furthermore, Akt has been shown to affect cell cycle progression and proliferative pathways and to possess a potential function in tumorigenesis and chemoresistance. In this study, we show that th...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409515/ https://www.ncbi.nlm.nih.gov/pubmed/15150572 http://dx.doi.org/10.1038/sj.bjc.6601876 |